Green tea health benefits.
Penn State researchers find green tea has potential value in fighting oral cancer. Photo by Nathan Cooke. Used with permission under Creative Commons license.

Researchers at Penn State say they have found another point to add to the growing list of green tea benefits, this time potential anti-cancer effect. Their research shows that a compound in green tea targets mouth cancer cells, without harming healthy cells. Read more at MicrobeWorld.org.

According to a news release from the researchers:

Earlier studies had shown that epigallocatechin-3-gallate — EGCG — a compound found in green tea, killed oral cancer cells without harming normal cells, but researchers did not understand the reasons for its ability to target the cancer cells, said Joshua Lambert, associate professor of food science and co-director of Penn State’s Center for Plant and Mushroom Foods for Health. The current study shows that EGCG may trigger a process in the mitochondria that leads to cell death.

“EGCG is doing something to damage the mitochondria and that mitochondrial damage sets up a cycle causing more damage and it spirals out, until the cell undergoes programmed cell death,” said Lambert. “It looks like EGCG causes the formation of reactive oxygen species in cancer cells, which damages the mitochondria, and the mitochondria responds by making more reactive oxygen species.”

(Source: Penn State News Office)

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